Theodore “Ted” Price, PhD, studies the role of pain plasticity mechanisms in the development of chronic pain, always with an eye toward generating novel therapeutics that can prevent or reverse the condition. He recently set up a new lab at the University of Texas at Dallas, US, where he is an associate professor in the School of Behavioral and Brain Sciences. Previously, he was an associate professor of pharmacology at the University of Arizona, Tucson, US. In 2014, Price won the Patrick D. Wall Young Investigator Award for Basic Science from the International Association for the Study of Pain. Neil Andrews, PRF executive editor, spoke by telephone with Price about his route to becoming a pain researcher, his experience setting up a lab for the second time, and the research projects he is working on now. Price also shared his perspective on how to identify promising targets for drug development, the pain field’s efforts thus far to develop new analgesics, and pain research trends he finds promising. Below is an edited transcript of the conversation.