Pyramidal neurons in the anterior cingulate cortex are shown with their cell bodies stained in red and their axon initial segments shown in green. These neurons are known to play a pivotal role in encoding the emotional aspect of pain. CAPS scientists study plasticity in these neuronal populations as pain becomes chronic.

The Center for Advanced Pain Studies (CAPS) is composed of eight founding UT Dallas faculty, affiliate faculty at UT Southwestern (UTSW), twelve postdoctoral fellows/research associates, and graduate students across multiple academic disciplines studying different facets of chronic pain and migraine.

Chronic pain is a significant problem of world-wide importance. The most common cause of long-term disability in the world, the annual cost of chronic pain in the U.S. is as high as $635 billion a year; more than cancer, heart disease, and diabetes care combined. CAPS is aggressively pursuing lines of research aimed at alleviating suffering from pain and improving the lives of people with chronic pain and/or migraine.

Pain research is one of the fastest growing research areas at UT Dallas, led primarily by faculty in Behavioral and Brain Sciences, but with participation from faculty from Natural Science and Mathematics, and the Erik Jonsson School of Engineering and Computer Science. These faculty are all research active and have consistently demonstrated their commitment and drive in pursuit of scientific discovery and new technology. Our goal is to create tomorrow’s pain therapeutics right here at UT Dallas in collaboration with our colleagues at UT Southwestern and throughout the world.